We examined CD64+ ATMs from visceral adipose tissue (VAT) and s.c. adipose tissue (SAT) from a bariatric surgery cohort with obesity, evaluating correlations with clinical metrics, divergence in CD64+ human ATM subtypes with stratification based on classical markers CD11c and MRC1 (CD206), and alignment of ATM subtype gene expression with existing data. The gene discussed is ITGAX; the disease is obesity due to melanocortin 4 receptor deficiency.