IL2RG and acute myeloid leukemia: To determine whether human AML mitochondria are processed by BMMs in vivo, we engrafted nonobese diabetic (NOD) SCID Il2rg-knockout (NOD.Cg.PrkdscidIL2rgtm1Wji/SzJ) (NSG) mice with human AML cells (Supplemental Figure 9, A and B) or human AML cells transduced with mCherry mito9 lentivirus (mCh-AML) to visualize mitochondria (Figure 5G).