In contrast, the miR‐130 inhibitor failed to inhibit hypoxia‐induced PASMC proliferation, migration and apoptotic resistance when co‐transfected with siPPARγ, suggesting that the miR‐130/PPARγ regulatory axis is an important link in the development of hypoxia‐induced PAH. The gene discussed is PPARG; the disease is pulmonary arterial hypertension.