PPARG and pulmonary arterial hypertension: In this study, we provide new evidence that FGF21 inhibits hypoxia‐induced proliferation and migration of PASMCs, reverses PASMC resistance to apoptosis, and ultimately improves pulmonary vascular remodelling and alleviates pulmonary hypertension by downregulating the negative regulatory effect of miR‐130 on PPARγ.