CD276 and neoplasm: However, the evidence of B7-H3 expression by MB is based on limited cases, cell lines instead of tissue, non-validated antibodies for B7-H3 detection [6, 8], single scoring systematics, lack of correlation with molecular tumor subtype, clinical data or microenvironment, or via analyses on 0.6–1 mm cancer tissue cores in a tissue microarray [7, 10]