MGMT and central nervous system cancer: Then age, WHO grade, IDH mutation status, 1p/19q status, MGMT status and DNAJC10 expression level were included in multivariate Cox regression analysis and results indicated that WHO grade, 1p/19q status and DNAJC10 expression level were independent prognostic factors in all three glioma cohorts (Figure 6A, multivariate Cox regression).