KLF4 and lung adenocarcinoma: Although the fact that FoxOs control the hepatic expression of KLF15 is revealed for the first time in the present study, there are several similar cases known for other KLF family members; for example, it is reported that KLF4 is a FoxO target in B cell (Yusuf et al., 2008), and so is KLF2 in T cell (Fabre et al., 2008) and KLF6 in lung adenocarcinoma (Sangodkar et al., 2012).