HLA-DRB1 and type 1 diabetes mellitus: When we analysed the genotypic distribution of HLA-DRB1 genes in GADA+, GADA–, IA2A+, and IA2A– people with T1D (Table 2), we observed a significant increase in the frequency of DRB1∗03/∗03 homozygote in GADA+ vs. GADA– patients (29.69% vs. 17.74%; P = 0.038; OR = 1.96; 95% CI: 1.08-3.54); however, the statistical significance was lost after Bonferroni correction (Pc = 0.228).