More recently, some small-molecule inhibitors of Fam20C (e.g., FL-1607 and 3r) have been reported to induce apoptosis as well as to prevent metastasis in breast cancer, which may reveal Fam20C as a druggable target for cancer therapy (Qin et al., 2016; Zhao et al., 2021). The gene discussed is FAM20C; the disease is breast carcinoma.