ZNF418 and esophageal cancer: At the same time, we found that zinc-finger protein 418 (ZNF418, context = -0.692), as a TOP3 prediction target gene, has been widely studied in tumors and plays an antitumor role in gastric cancer (Hui et al., 2018), liver cancer (Wang et al., 2019b), and esophageal cancer (Pu et al., 2017).