Among the SSI and Non-SSI groups, there were statistically significant differences in age (p < 0.001), BMI (p < 0.001), smoking (p = 0.002), diabetes (p < 0.001), ASA (p = 0.005), operation time (p < 0.001), estimated blood loss (EBL) (p < 0.001), number of fusion segments (p < 0.001), pre-operative HbA1c (p < 0.001), pre-operative albumin (p < 0.001), and pre-operative fibrinogen (p < 0.001). The gene discussed is ALB; the disease is diabetes mellitus.