Yang and his team also pointed out that the upregulation of LEF1-AS1 in NSCLC tissues affects the prognosis of patients with NSCLC; the group with high LEF1-AS1 was significantly correlated with tumor size (p = 0.037) and TNM stage (p = 0.04) (Yang et al., 2019). The gene discussed is LEF1; the disease is non-small cell lung carcinoma.