Factors associated with a significantly elevated EFS and OS in pediatric patients with B-ALL from univariate analysis were age, gender, chemotherapy protocol, WBC, PLT, risk group, immunophenotype, BCR/ABL1 fusion gene, MLL-r fusion gene and ETV6/RUNX1, prednisone response, D15 bone marrow status, D33- BM, and D15-MRD (Table 2). This evidence concerns the gene ABL1 and acute lymphoblastic leukemia.