(23) analyzed the prognosis of 244 ETV6/RUNX1-positive and 682 ETV6/RUNX1-negative children with B-ALL and showed that the EFS rate was significantly higher in the former than in the latter (82 ± 2% vs 72 ± 2%, P < 0.001), and ETV6/RUNX1-positive was an independent prognostic factor. Here, ETV6 is linked to acute lymphoblastic leukemia.