The following Western Blot analysis evidenced that gp96 protein was successfully delivered into the PS-BC cells by PR-BC-exo (Fold changes: 3.62 and 4.32, Figures 3B, C), and as expected, Real-Time qPCR analysis evidenced that PR-BC-exo did not affect gp96 mRNA levels in the PS-BC cells (Figure 3D). Here, HSP90B1 is linked to breast cancer.