HSP90B1 and breast cancer: To investigate the effects of gp96 on p53, we conducted Real-Time qPCR and Western Blot analysis, and our results hinted that gp96 merely suppressed p53 at protein levels (Fold changes: 0.63, Figures 2H, I) but not in the mRNA levels (Fold changes: 1.03, Figure 2G) in PS-BC cells.