The tumor infiltrating Rab37+CHI3L1+ cells were highly enriched with CD163+ M2 TAMs in the tumor sections from patients with advanced tumor stages, whereas early staged tumors displayed a low abundance of infiltrating Rab37+CHI3L1+CD163+ M2 TAMs and scattered intratumoral CHI3L1 (Figure 9A-B). This evidence concerns the gene CHI3L1 and neoplasm.