On the 7th day after MI, interleukin-13 (IL-13), chemokine (C-C motif) ligand 5 (CCL5) and chemokine (C-C motif) ligand 20 (CCL20, also known as MIP-3a) were decreased in the hypoxia-treated MI hearts, while matrix metalloproteinase-8 (MMP8) and chemokine (C-X-C motif) ligand 7 (CXCL7) were upregulated by hypoxia (Figure 3J) 20. This evidence concerns the gene MMP8 and myocardial infarction.