Among the genes (average fold change > 4) that mostly discriminated Cluster1A and Cluster2 (Figure 7A), the top two genes S100P and KRT17 were both prognostic markers in Andersen's CCA survival signature and Sia D's ICC recurrence signature, as well as the CD signature (Figure 7A). Here, KRT17 is linked to intrahepatic cholangiocarcinoma.