Examining the TIL fractions using flow cytometry (Figure 2B-D, and Figure S2), there was no difference in the number of CD45RO+CD4+ (tumor, 42.2 ± 15.8 versus normal, 41.87 ± 18.8) or CD45RO+CD8+ memory T cells (tumor, 37.2 ± 14.4 versus normal, 47.8 ± 17.9) in MPM compared with matched, nonadjacent uninvolved lung tissue (Figure 2E). Here, CD8A is linked to neoplasm.