Notably, the NCT-80 treatment for 72h induced apoptosis in H1299 and A549 NSCLC cells, as measured by decreases in un-cleaved PARP levels, upregulation of cleaved PARP (Cl-PARP) and Bax expression (Figure 3E), and increases in sub-G1 population (Figure 3F). This evidence concerns the gene BAX and non-small cell lung carcinoma.