USP39 and neoplasm: Univariate analysis with Cox regression showed that high expression of USP39 (HR = 1.775, 95%CI = 1.250–2.519, P = 0.001), advanced T stage (HR = 2.540, 95%CI = 1.785–3.613, P < 0.001), advanced pathological stage (HR = 2.449, 95%CI = 1.689–3.549, P < 0.001), and tumor status (HR = 2.361, 95%CI = 1.620–3.441, P < 0.001) were significantly associated with poor OS (Table 3).