UK Prospective Diabetes Study (UKPDS) Group UK Prospective Diabetes Study (UKPDS) Group UK Prospective Diabetes Study (UKPDS) Group Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33) Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33) Lancet. This evidence concerns the gene INS and type 2 diabetes mellitus.