Mogroside has an excellent biological development, which can inhibit the excessive activation of Signal Transducer and Activator of Transcription 3 (STAT3) and promote tumor cell apoptosis (Liu et al., 2018), and targeting STAT3 can improve tumor progression and anticancer immunity response (Lee et al., 2019); reversing emergency medical technician (EMT) and destroying the cytoskeleton to inhibit hyperglycemia-induced lung cancer cell metastasis (Guan et al., 2019). The gene discussed is STAT3; the disease is lung cancer.