HDAC9 and myocardial infarction: Zhang L. et al. (2018) reported acute HDAC effects as positive and negative regulators for pathological cardiac remodelling. Wang J. et al. (2020) uncovered the histone modification profile in the early stage of MI of mice and proved that the modulation of histone modifications could involve inflammation and angiogenesis through adjusting promoters and super enhancers and joining cardiac remodelling pathological processes.