ORN and Pam-3-Cys are ligands to the mainly monocyte expressed TLR7 and TLR1/2, respectively, and induced higher secretion of RANTES in the EBV CF+ group compared to both the EBV CF- group and healthy controls, discriminating between the two patient groups (Figure 1). The gene discussed is CCL5; the disease is cystic fibrosis.