Conversely, the dopamine D2 receptor agonist bromocriptine, approved for use to treat diabetes because of its ability to reduce hyperglycemia in individuals with type 2 diabetes mellitus (Barnett et al., 1980), decreases adiposity in both humans (Meier et al., 1992) and other mammals (Cincotta et al., 1991, 1997). The gene discussed is DRD2; the disease is type 2 diabetes mellitus.