APC and melanoma: To our surprise, we did not find any correlation between APC/CTNNB1 somatic mutation and lymphocyte score in the TCGA SKCM cohort, a consensus and composite measurement of the density of peritumoral and intratumoral TILs, based on the hematoxylin and eosin analysis of representative tissue sections from the TCGA SKCM melanoma specimens [17].