From day 4–6 of the disease, the results of univariate logistic regression analysis showed that the indicators related to the prognosis of severe dengue were platelets ≤ 50 G/L, AST/ALT > 400 U/L, serum albumin < 35 g/L, bilirubin TT > 17 μmol/L, PT <70% and fibrinogen < 2 g/L. This evidence concerns the gene GPT and dengue disease.