Genotoxic therapies, such as chemo‐ and radiotherapy, cause high level of DNA damage in quickly proliferating cells and often achieve tumor suppression by leading cells into senescence—a stable form of growth arrest dependent on the upregulation of cyclin‐dependent kinase (CDK) inhibitors p16 and p21 (Rodier & Campisi, 2011). This evidence concerns the gene CDKN2A and neoplasm.