LHCGR and type 2 diabetes mellitus: In mice, the offspring of GDM mothers showed alterations in the methylation pattern of the DMRs of the ankyrin repeat and ph domain 2 (Agap2), 1‐phosphatidylinositol‐4,5‐bisphosphate phosphodiesterase beta‐1 (Plcbr1), Hnf1b, guanine nucleotide‐binding protein, alpha stimulating (Gnas) fructose‐bisphosphatase 2 (Fbp2), cadherin‐13 (Cdh13), wingless‐type 2 (Wnt2), Kcnq1, luteinizing hormone/choriogonadotropin receptor (Lhcgr), and iroquois‐class homeodomain protein (Irx3) genes, which eventually led to increased susceptibility to T2D in adulthood.136