CRP and Sepsis: Study conducted by Seidel et al. for predicting late-onset sepsis by body surface screening had pooled sensitivity of 41% (95% CI 17–70%) and specificity of 56% (95% CI 34–76%), whereas another included study in our review for predicting late-onset sepsis by clinical and laboratory evaluation had shown sick appearance (OR 5.7, 95% CI 1.1–29.1), CRP > 0.75 (OR 5.4, 95% CI 1.1–26.3)), neutrophil to lymphocyte ratio > 1.5 (OR 6.7, 95% CI 1.2–38.5) as the chief predictors with model AUC of 0.92 [22].