Strikingly, arachidonic acid is a known PPARα- and γ-activating ligand (Fang et al., 2007), which is released after injury or irritation as an inflammatory mediator (Tavolari et al., 2008), and has been previously linked to cancer progression (Avis et al., 2005; Chang et al., 2013). The gene discussed is PPARA; the disease is cancer.