Crude model: Cox model unadjusted, LME model adjusted for sampling time; Model 1: Cox and LME models adjusted for age, sex; Model 2: Cox and LME models adjusted for Model 1 plus body mass index, hemoglobin, ferritin, and dialysis vintage; Model 3: Cox and LME models adjusted for Model 2 plus creatinine, single-pool Kt/V, phosphorus, parathyroid hormone, and C-reactive protein; Model 4: Cox and LME models adjusted for Model 3 plus vascular access type, presence of diabetes mellitus, hypertension, cardiovascular disease, and other comorbidities. The gene discussed is CRP; the disease is diabetes mellitus.