However, only some circulating inflammatory markers were associated with myocardial fibrosis (e.g. interleukin-6, interleukin-4, and monocyte attractant protein-1), the degree of hypertrophy (e.g. fractalkine), or diastolic dysfunction (e.g. interferon-γ-inducible protein 10, interleukin-10, and transforming growth factor-β1) (32). Here, IL4 is linked to Myocardial fibrosis.