CD36 and neoplasm: Interestingly, treating in vitro-generated TAMs with etomoxir to inhibit β-oxidation significantly reduces the expression of TAM-associated genes (including Arg1, Vegf, and Pparg), while TAM-specific CD36 KO mice successfully contained EL4 tumor growth, demonstrating that targeting lipid metabolism in TAMs may be an effective strategy to combat tumor growth in vivo [101].