Additionally, immunofluorescence of Iba1 on detection of microglial activation and immunofluorescence of tyrosine hydroxylase on assessment of dopaminergic neuron loss revealed that depletion of miR-132-3p may alleviate MPTP-induced dopaminergic neurodegeneration and neuroinflammation of PD mouse models. The gene discussed is TH; the disease is Parkinson disease.