To determine whether the inhibitory effect of STING signaling on in vivo tumor growth might be due, at least in part, to IFN production, NSG mice bearing A673 (C1) tumors received two intratumoral injections of IFN-β or IFN-λ (50 ng or 25,000 IU each over a 7-d span) and tumor growth was compared with that of tumors injected with solvent only. This evidence concerns the gene IFNA1 and neoplasm.