Immunostaining with rabbit polyclonal phosphorylation–independent anti-TDP-43 antibody 10,782–1-AP revealed cytoplasmic inclusions of aggregated TDP-43 protein in the amygdala of only three of 33 DS subjects (9.0%), who died at 59, 61, and 65 years of age. Here, TARDBP is linked to Dravet syndrome.