HOXB13 and cancer: In total, 813 kidney cancer cases and 4497 controls were genotyped for HOXB13 mutation p.G84E. The mutation p.G84E was found in three (0.4%) of the cancer cases and in six (0.1%) of the controls (OR = 2.8; 95% CI 0.69–11.11; p = 0.3) (Table 2).