In a recently published study, DSS-induced colitis found upregulation of inflammatory-related proteins S100A8, S100A9 (also known as myeloid related protein (MRP) 8 and MRP14), and lipocalin-2 (Lcn2, also known as neutrophil gelatinase-associated lipocalin) in the brain. This evidence concerns the gene S100A8 and colitis.