KDR and Carcinoma, Lewis Lung: The weight and size of tumors in control, DHI, PAC, and AAC-treated groups were shown in Fig. 6B and C. To evaluate the effect of AAC in angiogenesis inhibition, Lewis lung carcinoma cells were transplanted into VEGFR2-Luc mice, where luciferase expression was driven by the VEGFR2 promoter, allowing direct observation of angiogenesis using in vivo bioluminescence intensity.