IGHG3 and malaria: Individuals with higher levels (> 75th percentile) of anti-GLURP IgG3 antibodies were also older and presented a higher time of residence in the malaria-endemic areas (mean ± standard deviation: 46 ± 15 versus 36 ± 16, P = 0.02) (Fig. 11), but did not show different levels of parasitaemia when compared to those of low IgG3 antibody levels.