REN and cancer: These pathways include JAK/STAT Signaling, Renin-Angiotensin Signaling, Molecular Mechanisms of Cancer, IL-8 Signaling, CXCR4 Signaling, LPS-Stimulated MAPK Signaling, EGF Signaling, PEDF Signaling, NF-κB Activation by Viruses, and B Cell Receptor Signaling (Fig. 4a).