In 2017, Zhao et al. measured LRRK2, p-LRRK2S935, VPS35, GBA, MPR300, and IGF2R levels in post-mortem brain samples from PD patients carrying LRRK2 mutations to study the relationship between LRRK2 and retromer dysfunction in LRRK2-associated PD [14]. Here, IGF2R is linked to Parkinson disease.