According to the clinical diagnosis, including disease history, clinical presentation, dementia scores, alpha-synuclein pathological feature, and phosphor-Tau- and Aβ-related pathological features, the cases were classified as the control, PDD, and DLB patients by their clinical doctors (Additional file 1: Table S1), which were used as the three study groups investigated here. This evidence concerns the gene MAPT and Lewy body dementia.