CXCL2 and IL6 with down-regulated in STS were significantly positively related to macrophage, neutrophil, cytotoxic cell, dendritic cell (DC), interdigitating dendritic cell (iDC), plasmacytoid dendritic cell (pDC) (all r > 0.3) (Fig 9B and 9C), and HELLS with up-regulated in STS was comparatively negatively correlated with macrophage, neutrophil, cytotoxic cell, DC, iDC, pDC (all r < -0.3) (Fig 9D) Consistency of results and significant association with immune cells were not demonstrated in STMN1, EPAS1 and NQO1. The gene discussed is NQO1; the disease is telomere syndrome.