Currently, neuroimaging biomarkers (e.g., medial temporal lobe atrophy, decreased glucose metabolism in the temporo-parietal lobe, amyloid-β deposition) and neurochemical biomarkers (e.g., abnormal amyloid-β and tau proteins in cerebrospinal fluid and plasma) are widely used for the detection of AD [11–14]. This evidence concerns the gene MAPT and Alzheimer disease.