Ni et al. show that breast cancer‐derived exosomal lnc‐SNHG16 can enhance the activation of the TGF‐β1/SMAD5 pathway through the miR‐16‐5p/SMAD5 regulatory axis, thereby inducing the expression of CD73 in Vδ1 T cells and leading to malignant tumour progression.54 Here, SMAD5 is linked to breast carcinoma.