IL6 and rheumatoid arthritis: The NFKBIE locus is associated with rheumatoid arthritis (RA),43 which is characterised by IL-6 mediated autoimmunity and can be treated with IL-6 targeting drugs.44,45 We performed a colocalisation analysis of molecular QTL and GWAS using enloc.46 On average the posterior colocalisation probability was 70% at the sentinel SNP rs730775 (Figure 4a), supporting a shared causal variant for the majority of the CpG sites.