Unfortunately, no studies have yet examined the relationship between CagA and VacA in the development of gastric MALT lymphoma, but VacA induces apoptosis by forming a vacuole and release of cytochrome c from mitochondria and appears to inhibit the development of gastric MALT lymphoma [71, 72]. The gene discussed is S100A8; the disease is gastric mucosa-associated lymphoid tissue lymphoma.