We found a strong increase of number of spikes measured in 24 h in Scn1a ± mice after the thermal stress but not in the Scn1a ± eEF2K−/− mice, suggesting that eEF2K deficiency reduced the susceptibility to epilepsy of the Scn1a ± mice (Fig. 2a right panels, b). Here, SCN1A is linked to epilepsy.