IGF2BP2 and head and neck squamous cell carcinoma: The findings in this study have shown a high expression of IGF2BP2 in HNSCC tissues, and higher IGF2BP2 expression was significantly correlated to pathological N classification, LN metastasis and poor OS probability, indicating that IGF2BP2 could function as a prognostic biomarker in HNSCC, and plays a potential role in lymphatic metastasis of HNSCC.