Puram et al. [57] investigated the intertumoral heterogeneity and metastasis between primary HNSCC tumors and matched LNs using single-cell transcriptomic analysis, and they found that Slug was the only EMT-related TF detected in HNSCC cells and closely correlated with the program across tumors. The gene discussed is SNAI2; the disease is head and neck squamous cell carcinoma.