First, we standardized the acquired data (Additional file 2: Fig. 2A–C), and then compared the NPC samples with normal tissues and found that there were a large number of differentially expressed m6A-modified related genes in NPC, such as ALKBH5 as m6A erasers (p < 0.001), YTHDF3 as m6A readers (p < 0.01), and m6A as m6A METTL3 of writers (p < 0.05) (Fig. 3A). The gene discussed is YTHDF3; the disease is nasopharyngeal carcinoma.